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Is Enough for the ACC for Now

Rachel Ehrenberg is an interdisciplinary sciences and chemistry writer, with Science News, based in Washington, D.C.<br> SALT LAKE CITY -- Utah men's basketball coach Jim Boylen was hoping for one more year to rebuild.One of the region’s most <b>intractable</b> conflicts may be nearing a close, thanks to the determination of the <b>prime</b> minister, yet ending violence will not end tension. About 20 years ago, scientists discovered the gene that causes Huntington’s disease, a fatal neurodegenerative disorder that affects about 30,000 Americans.<br> The mutant form of the gene has many extra DNA <b>repeats</b> in the middle of the gene, but scientists have yet to determine how that extra length produces Huntington’s symptoms.In a new step toward answering that question, MIT biological engineers have found that <b>the</b> protein encoded by this mutant gene alters patterns of chemical modifications of <b>DNA.</b><br><img src="http://idleeflthoughts.files.wordpress.com/2009/05/best-job.jpg"><br> This type of modification, known as methylation, controls whether genes are turned on or off at any given time.The mutant form of this protein, dubbed “huntingtin,” appears to specifically target <b>genes</b> involved in brain cell function. Disruptions in the expression of <b>these</b> genes could account for the neurodegenerative symptoms seen in Huntington’s disease, including early changes in cognition, says Ernest Fraenkel, an associate professor of biological engineering at MIT. Fraenkel’s <b>lab</b> is now investigating the details of how methylation <b>might</b> drive those symptoms, with an eye toward <b>developing</b> potential new treatments. “One could imagine that if we can figure out, in more mechanistic detail, what’s causing these changes in methylation, we might <b>be</b> able to block this process and restore normal levels of transcription early on in the patients,” says Fraenkel, senior author<br><img src="http://3.bp.blogspot.com/-PaAipF_k5FU/T3UOFODbYhI/AAAAAAAABGA/ErQrHoLqdOE/s1600/Internet-wtf.jpg"><br> of a<br><img src="http://lh3.ggpht.com/_dlkAw43cLC0/SY_cTmXJaEI/AAAAAAAADHQ/TfPwow00H64/s800/14-Lovely-Hearts-for-St-Valentines-day-sandwich.jpg"><br> paper <b>describing</b> the findings in this week’s issue of the Proceedings of the National Academy of Sciences.Lead author of the paper is Christopher Ng, an MIT <b>graduate</b> student in biological <b>engineering.<br></b> Other authors are MIT postdoc Ferah Yildirim; recent graduates Yoon <b>Sing</b> Yap, Patricio Velez and Adam Labadorf; technical assistants Simona Dalin and <b>Bryan</b> Matthews; and <b>David</b> Housman, the Virginia and D.K. Ludwig Professor <b>of</b> Biology.Unexpected<br> patternsDNA methylation has a major <b>impact</b> on genetic expression: Genes that are methylated at particular sites are usually dormant, because the methyl groups deny access to the proteins<br><img src="http://i44.tinypic.com/68dmav.jpg"><br> needed to copy DNA’s instructions and carry them to the rest of the cell.<br> For a long time, scientists believed that DNA methylation patterns changed during embryonic development <b>and</b> then <b>remained</b> constant in adulthood. However, DNA methylation is emerging as important to a <b>wide</b> range of normal cell activity.In<br> the new study, the MIT team measured changes in methylation patterns during early stages of Huntington’s <b>disease</b> in <b>cells</b> derived from a brain region called the striatum in mouse embryos.<br> This region, where planning of movement occurs, is severely affected by Huntington’s disease. “We’re very interested in the earliest <b>phases,</b> because that’s when there’s the most hope that you could either slow down or <a href = "http://forex-growth-bot.webs.com">forex growth bot </a> of the disease, and allow people to live healthy lives <b>much</b> longer,” Fraenkel says. “By the time there is much <b>more</b> severe neurodegeneration, it’s unlikely that you’re going to <b>be</b> able to reverse the damage.”Fraenkel<br> and Ng were surprised to find a dramatic difference in methylation patterns between cells with normal and mutant forms of the huntingtin protein.<br> Some genomic sites gained methylation, while others lost it.<br> Many of the affected sites were in regions that regulate the expression of nearby genes necessary for neuron growth and survival.Turning<br> genes off and onAfter observing the changing methylation patterns, the MIT team identified many proteins that tend to bind to the DNA sites where those changes take place. These proteins include Sox2 and others <b>known</b> to regulate genes involved in neuronal activity, <b>including</b> growth of the <b>neurons.</b> The new findings go a <b>long</b> way toward explaining <b>how</b> the extra DNA repeats in the mutant form of the huntingtin gene might bring about disease, <b>says</b> Mark Mehler, a professor of neurology at the Albert Einstein College of Medicine.<br> “People have not <b>had</b> a <b>good</b> sense, until this paper, <b>of</b> what these repeats might be doing,” says Mehler, who<br><img src="http://image.shutterstock.com/display_pic_with_logo/498865/498865,1298958422,1/stock-vector-sad-emoticon-72187144.jpg"><br> was not part of the research team. “What <b>this</b> study<br><img src="http://4.bp.blogspot.com/-PplBaVLO-MU/T_OvdNfFsKI/AAAAAAAACXw/Y2osG1LVCTg/s1600/lovely_%2Brose_%2Bimages.jpg"><br> has done is <b>demonstrated</b> a mechanism <b>by</b> which expanded repeats can alter gene expression.”The<br> researchers are now studying whether huntingtin affects other <b>modifications</b> of DNA and histones, the proteins around which DNA is wound.<br> Together, these <b>might</b> cause genes to be turned on or off inappropriately, Fraenkel <b>says.<br></b> The <b>researchers</b> are also working with mouse models at different stages <b>of</b> Huntington’s disease to track how the methylation patterns change as the disease <b>progresses.<br></b> “That also gives us an opportunity to do interventions and test <b>whether</b> affecting particular proteins influences the progression <b>of</b> the disease,” Fraenkel says.The<br> research was funded by the National <b>Institutes</b> of Health.<br> In <b>Derek</b> Waters’s <b>“Drunk</b> History” <b>on</b> Comedy Central, actors like Jack Black<br><img src="http://media.outsideonline.com/images/BestPlaceslogo_12.jpg"><br> and Owen Wilson re-enact historical accounts as described by inebriated narrators.     If you <b>have</b> running water coming through the holes, try to wait for a dry spell to do the repair.<br> Some of<br><img src="http://images2.fanpop.com/image/photos/8800000/baby-girl-babies-8856968-377-322.jpg"><br> these hydraulic repair cements<br><img src="http://media.treehugger.com/assets/images/2011/10/bog_design2Barchitec_550x550.jpg.644x0_q100_crop-smart.jpg"><br> will work if there is moving water, but it's not guaranteed. There’s no slowing down for the Nascar driver Jimmie Johnson as he tackles different sports. A war funding bill passed the Senate overwhelmingly yesterday, but the 91 to 5 vote came after a fractured process that included objections from Republicans and Democrats alike, and required President Obama to intervene repeatedly to lobby members of his own party for his foreign policy vision.<br> U.S. stocks plunged last week, giving the Dow Jones industrial average its first seven-day<br><img src="http://i.istockimg.com/file_thumbview_approve/16349486/2/stock-illustration-16349486-lovely-floral-card.jpg"><br> loss since 2008, after reports showed slower-than-estimated growth in jobs and factory orders. On Sept. 16, 1920, a bomb hidden inside a horse-drawn <b>carriage</b> exploded in the heart of Manhattan's financial district, <a href = "http://micro-niche-finder.webs.com">micro niche finder review </a> of people. That long-forgotten bombing was the deadliest terrorist attack in New <b>York's</b> history until Sept. 11, 2001, when it became a renewed subject of<br><img src="http://2.bp.blogspot.com/-1B4d-Dtf12c/UEs1PWZZ8lI/AAAAAAAABxQ/2RhB8dO-RH8/s1600/Black-Sad-Sad-Sad-Sad-Sad-Sad-Sad-The-Pictures-are-a-Disaster.jpg"><br> curiosity. Mr. Asciu’s work appeared for decades in publications like The New York Times and The New Yorker. Agnetha Faltskog<br><img src="http://24.media.tumblr.com/81e53912fe2e1db579524cd6aa1b4acc/tumblr_mflxag5MK11qinh7xo1_500.jpg"><br> of Abba is back with a new album, her first record of new material <b>since</b> 1987.     <b>ISLAMABAD,</b> PAKISTAN - A Pakistani <b>court</b> on Thursday gave the central government three more weeks to determine whether a U.S. official facing murder charges qualifies for diplomatic immunity. The ruling prolongs a diplomatic crisis threatening the two nations' counterterrorism alliance. A Fula and Style fashion show.<br> Photo courtesy of Aminata Kane Syrian troops backed <b>by</b> pro-government <b>gunmen</b> swept into a Sunni village in <b>the</b> mountains near the Mediterranean coast on Thursday, killing dozens of people, including women and children, and torching homes, activists said. Read full article >>     PARIS -- L'Oreal SA, the world's largest beauty products company, has a Frenchman at its helm <b>for</b> the first time in almost two decades after shareholders on Tuesday approved the appointment of Jean-Paul Agon to succeed departing British CEO Lindsay Owen-Jones. Edelman Leather cooked <b>up</b> a scheme with architect Jack Travis to engage <b>his</b> class of Pratt Institute interior-design graduate students in a special project. Same-sex marriage rights were not, as is commonly believed, a natural consequence of the gay liberation <b>movement</b> that emerged in the late ’60s.     The Spanish rivals <b>Real</b> Madrid and Barcelona and the German giants Bayern Munich and Borussia Dortmund avoided each other when the matchups were drawn.<br> There’s never been any doubt that pregnancy drastically changes a woman’s body: She gains weight, her center of gravity shifts <b>and</b> connective tissues become looser. But it also affects how a woman moves.    <br> Applicants with three A*s <b>at</b> A-level are 20% more likely to get offer if they are white than if they are from ethnic minorityPeople applying <b>to</b> study medicine at Cambridge University with three A*s at A-level are more than 20% more likely to be given an offer <b>if</b> they are white than if they are from an ethnic minority, according to new data released by the institution.Cambridge University released the <b>detailed</b> admissions data, covering <b>2010</b> to <b>2012,</b> for medicine only in response to a freedom of information request. The university refused a similar request a <b>few</b> weeks <b>before,</b> which covered more subject areas, on the grounds of cost.The data, which covers applications from within the UK by people <b>who</b> declare their ethnicity, shows that 329 out of 586 white applicants for medicine who went on to achieve three A*s were given an offer of a place, versus 190 of 412 applicants from ethnic minorities – representing success rates of 56% and 46% respectively.<br> The difference between the two groups is <b>statistically</b> significant.Both Oxford <b>and</b> Cambridge have been challenged by <a href = "http://productreviewer4u.webs.com/fat-burning-furnace">fat-burning-furnace </a> campaigners to do more to get students from ethnic<br><img src="http://images2.fanpop.com/image/photos/14400000/Pretty-Little-Liars-Cast-Instyle-Makeover-Shoot-hanna-marin-14429238-500-632.jpg"><br> minorities into their institutions, particularly as the headline admissions figures <b>for</b> both show a substantial gap <b>in</b> success rates between students of different ethnicities.The<br> universities have said this gap <b>is</b> explained in large part by students from <b>ethnic</b> minorities disproportionately applying for the most competitive subjects, such as medicine – but these figures show that even within the competitive subjects white students are <b>more</b> likely to receive offers.Cambridge's race gap for <b>medical</b> applicants is substantially smaller than that of its rival, Oxford University. Figures released to the Guardian under the Freedom of Information Act, <b>published</b> last month, show white students applying for medicine who went<br><img src="http://1.bp.blogspot.com/-33MnKBjGZPo/UQv8EBotT8I/AAAAAAAAARM/MbDw3SqGJbE/s1600/2.jpg"><br> on to achieve <b>three</b> A*s were 94% more likely to be offered a place at Oxford than those <b>from</b> ethnic minorities.A-levels are <b>only</b> one of several factors taken into account by admissions tutors for medicine at both universities.<br> Applicants are also required to take a specific entrance exam, the bioMedical admissions test, while work experience and performance at interview are also <b>factored</b> in to whether to make an offer. Those handling <b>applications</b> may also be unaware of <b>the</b> ethnicity of prospective <b>applicants</b> rejected before interview.A Cambridge University spokeswoman said analysis of applications<br><img src="http://api.ning.com/files/di3TKwTHv5A1JCvTPba0sQPAYtgTZCWJPlXstje4phMxWlLXnV80aH2IbvxoGB8YyZvybFY8fApkLQY6R*y1iGbKgUwJtN4T/101waystosayILOVEU.jpg"><br> based on A-level grades <b>"ignores</b> a significant number of relevant variables" and is <b>therefore</b> "superficial"."Admissions<br> decisions are based on students' ability, commitment and their potential to <b>achieve,"</b> she said. "Our commitment to improving access <b>to</b> the university is longstanding and <b>unwavering â€¦</b> [and] we aim to ensure that anyone with the ability, passion and commitment to apply <b>to</b> Cambridge receives all the support necessary for them to best demonstrate their potential."She<br> added Cambridge had run initiatives to encourage gifted students from minority backgrounds to apply to Cambridge since 1989.Oxford University declined <b>to</b> comment on the difference in size of the medical race gap<br><img src="http://static.freepik.com/free-photo/fart-forbidden-zone_2694850.jpg"><br> of applicants <b>between</b> itself and Cambridge University, but said in an earlier statement it constantly reviewed the race gap of its applicants."Oxford<br> University is committed to selecting the very best students, regardless of race, ethnicity, or any other factor," a spokeswoman said."This is not only the right<br><img src="http://3.bp.blogspot.com/-bzEbUiqgJx8/UKm0UsWGH5I/AAAAAAAAADk/kB15x9_o0g8/s1600/love-inspirational-daily.jpg"><br> thing to do but it <b>is</b> in our own interests. Differences in success<br><img src="http://cdn.sheknows.com/articles/2011/01/baby_girl_face.jpg"><br> rates between ethnic groups are therefore something we are continuing to examine carefully for possible explanations."The Oxford spokeswoman also noted Cambridge made more use of students' grades at AS-level than does Oxford, and said ethnic minorities were well represented at the university, making up 22% of all students and 13% of UK undergraduates.University of CambridgeHigher educationMedicineRace<br><img src="http://i1.mirror.co.uk/incoming/article1452655.ece/ALTERNATES/s927b/Monster%2BGirl.%2BAustralian%2BGrand%2BPrix,%2BSaturday%2B17th%2BMarch%2B2012"><br> in educationRace issuesEqualityJames BallKurien Parelguardian.co.uk<br> © 2013 Guardian News and Media Limited or its affiliated <b>companies.</b> All rights <b>reserved.</b> | Use of this content is subject to our Terms & Conditions | More Feeds The Highway Loss Data Institute has found that the F-250<br><img src="http://images2.fanpop.com/image/photos/14400000/Pretty-Little-Liars-Cast-Instyle-Makeover-Shoot-hanna-marin-14429238-500-632.jpg"><br> is more likely to be stolen than any other vehicle.     <a href = "http://productreviewer4u.webs.com/google-sniper">google sniper </a> researcher created <b>a</b> <b>massive</b> botnet by hijacking about <b>420,000</b> Internet-accessible embedded devices with default or no login passwords and used it to map the entire Internet. The botnet, which was dubbed Carna after the Roman <b>goddess</b> of physical health, ran between March and December <b>2012,</b> and was used to <b>perform</b> "the largest and most comprehensive IPv4 [Internet Protocol version 4] census ever," the researcher said Sunday on a website dedicated to the project.<br> <b>While</b> fission reactors are among the most intricate systems in the world, engineering them to run <b>reliably</b> and economically is only a starting point. Fission technology must <b>integrate</b> not only with the energy <b>grid,</b> but with <b>society</b> as a whole, meeting stringent safety, security <b>and</b> environmental expectations with oversight from well-versed managers and policymakers.Advancing<br> this complex integration is a primary mission of MIT <b>NSE’s</b> Center for Advanced Nuclear Energy Systems (CANES), which conducts a combination of front-line technology development, <b>groundbreaking</b> strategic studies and professional education for nuclear technologists<br><img src="http://25dip.com/wp-content/uploads/2012/11/1260894977149-annual-dog-show.jpg"><br> and managers.As the focal point of MIT NSE’s wide-ranging work in fission, CANES embodies the department’s science-systems-society approach to nuclear energy, playing a central role in the worldwide nuclear community and its<br><img src="http://images.wisegeek.com/dog-with-suds.jpg"><br> ongoing development and improvement. CANES research spans many disciplines, including fission process physics, thermal hydraulics, materials science, systems reliability and probabilistic safety analysis, but maintains a unified perspective that is rare in the academic world.“Perhaps uniquely among universities, we are able to address all aspects of the reactor — MIT has a well-known reputation for addressing nuclear <b>systems</b> as a whole, as opposed to just <b>the</b> individual <b>pieces,”</b> explains Mujid Kazimi, TEPCO Professor of Nuclear Science and Engineering and <b>Professor</b> of Mechanical Engineering, who <b>has</b> directed CANES since its founding in 2000. Kazimi oversees more than 20 affiliated faculty and <b>research</b> scientists, <b>and</b> more than 60 participating graduate students, all of whom contribute to the Center’s prolific production of research, analysis, symposia and classes.This <b>broad</b> <b>reach</b> has enabled interdisciplinary investigation of nuclear power’s overall future and the fuel cycle, and<br><img src="http://images2.fanpop.com/image/photos/9100000/Little-Lovely-Girl-sweety-babies-9180976-550-550.jpg"><br> technological advances like improvements to light-water reactors (LWRs) and studies <b>of</b> novel reactor designs cooled by salts, liquid metals or gases. The systemic perspective means that topics like reactor <b>maintenance</b> and safety, regulation and non-proliferation are always in mind.<br> These issues in turn drive development of new materials and structures, which can significantly impact <b>reactor</b> performance <b>and</b> effectiveness.“You can’t understand the entire system without being able to<br><img src="http://spadogbotanicals.com/wp-content/uploads/puppy1.jpg"><br> look both ways — at internal features <b>and</b> external impact,” Kazimi observes. “That’s essential to improving society’s readiness to accept the technology.<br> In our<br><img src="http://24.media.tumblr.com/81e53912fe2e1db579524cd6aa1b4acc/tumblr_mflxag5MK11qinh7xo1_500.jpg"><br> report on the future of the nuclear fuel cycle, for example, we pointed out reactor concepts that <b>might</b> <b>create</b> a more-affordable closed fuel cycle, and also be more acceptable on external considerations<br><img src="http://photoity.com/wp-content/uploads/2010/07/20-Examples-Of-Lovely-Baby-Animal-Photography-1.jpg"><br> like fuel resource needs and volume of waste. That came about because we were <b>thinking</b> of both sets of factors.”Read the full

A documentary that teenagers helped produce follows Dedric Hammond of Harlem, a former prisoner who tries to prevent conflicts from ending in gunfire.     The NBA remains the industry leader among men’s professional sports leagues for racial and gender hiring practices, according to a study released Tuesday.    Toyota has tapped a former executive at U.S. rival General Motors to join its board, the first time in the Japanese automaker’s 76-year history it is appointing directors from outside the company. The answer to the double whammy of investment losses in 2008-9 and low interest rates now on savings accounts is not some dubious new product. Federal regulators have ordered the immediate inspection of throttles on small personal jets manufactured by Eclipse Aviation after one plane made an emergency landing in Chicago on June 5. Landon Donovan has not played for the national team since last summer and was passed over by Coach Jurgen Klinsmann after Donovan took a sabbatical from soccer.     Mads Mikkelsen plays a teacher suspected of being a pedophile in “The Hunt,” set in a Danish village.     Soft diets of today have led to dental problems As Americans live longer and the stigma of psychological help diminishes, more elderly people are trying therapy to alleviate problems they face late in life.     Kidnappers freed two Syrian bishops on Tuesday who had been abducted in the northern city of Aleppo, a church official said, but the identities of their kidnappers remained uncertain.     Five MIT faculty members — Alfredo Alexander-Katz; William Detmold; Liang Fu; William A. Tisdale; and Michael Williams — have been named recipients of the 2013 Early Career Award of the Office of Science of the Department of Energy (DOE).Now in its fourth year, the Early Career Awards support the development of individual research programs by outstanding scientists who are in the early stages of their careers, and stimulates research careers in the disciplines supported by the DOE’s Office of Science. Across the Office of Basic Energy Sciences divisions, 61 awards were made from about 770 proposals that went out for peer review. The body responsible for deciding on the future of London’s Olympic Stadium confirmed on Wednesday that Leyton Orient have mounted a legal challenge to the decision to name Premier League club West Ham United the preferred bidder. BOGOTA, COLOMBIA — A retired police major who is in exile in Argentina was deposed Tuesday by the Colombian attorney general’s office after he accused President Álvaro Uribe’s brother of having led a right-wing paramilitary group in the early 1990s. Prince William regional jail officials have joined a federal system to tighten their screening of inmates’ immigration status and potentially deport those in the United States illegally. All India Trinamool Congress chief Mamata Banerjee supports government on Sri Lanka. For Pope Francis to change the Vatican, he must tame a hierarchy whose branches are run like medieval fiefs and whose supplicants vie for access and influence. Click here to have the Fiver sent to your inbox every weekday at 5pm, or if your usual copy has stopped arrivingDOESN’T RING A BELLEDear Sturdy Short-Haired Cat-Loving Fiver,I trust this letter finds you in good health. In an instance of uncharacteristic and frankly implausible forward-planning necessitated by this riff, I write because I am preparing a story on the opening match of England’s Euro 2013 campaign against Spain. I don’t need to tell you, dear cousin, that we are talking here about women’s football, of which your poor old Fiver knows nothing. Not a sausage. Something about belles? No idea. This is going to be one of those stories that requires “contacts”, and since $exually Repressed Morris Dancing Fiver is still at that pottery retreat, you are the only hope. Please forward all information ASAP.Best wishes,Fiver.*****Dear Fiver,If you want to cover women’s football, you might have done better than a letter to your tired, cliched and, actually, quite offensive cousin. Oh. I’m sure your readers must expect more. Oh.SSHCLF*****Dear SSHCLF,Your last letter was most upsetting, particularly in reference to readers. Please forex growth bot taunt the Fiver with the plural.Help!Very best,Fiver*****Dear Fiver,All right. You could mention that the England team were on an 11-match unbeaten run until meeting the hosts, Sweden, in a friendly last week, which they lost 4-1. It was disappointing, especially as the defender Sophie Bradley was knacked in the process and will definitely miss the game against Spain. There’s still some doubt about the fitness of other key players in the camp, including the captain Casey Stoney and Steph Houghton, not to mention Kelly Smith. But the mood in the camp seems to be good. “We have done a lot of work on the pitch [since losing to Sweden], a lot of analysis and basically just been relaxing,” Hope told proper journalists this week. “The first group game is always quite tense. I’m sure both teams are raring to go; both teams want to do well in and with that comes a few nerves.” You could also make use of the wise words of the Chelsea forward Eni Aluko. “It was a good thing to play in a friendly that didn’t mean much and try to analyse the game and learn from our mistakes. We could have gone into the tournament thinking we were invincible.” Imagine!SSHCLF*****Dear SSHCLF,Who is Hope?Fondest wishes,Fiver*****Dear Fiver,You are an idiot.SSHCLF*****Dear SSHCLF,Aha! Hope Powell, the Mr Roy of women’s football. There is a crucial difference though, dear cousin. A dreadful lack. Mr Roy always spells out in clinical tactical detail what is good and bad about his opponents – “they are a good side”, for instance; “they like to play football.” But it says here that Hope Powell and her Spanish counterpart have simply said that they know “everything” about one another’s teams. How is a tea-time football email supposed to pass this off as its own?Please send more information – do you speak Spanish? – at the earliest opportunity.Fiver*****Dear Fiver,“Spain are a very technical team, very similar to the men in fact, so they will be a big threat and we will have to be at our best. In 2010 their under-17s won the European Championship and a lot of those players are coming through. It’s their first major tournament since 1997 so for them this is a massive leap. They have got a lot to prove and they are capable of it. They are here for a reason, it was difficult to qualify for this tournament.” It took me two minutes to copy and paste this quote from Hope Powell off the BBC website. And Uefa has got quotes from Ignacio Quereda, too. “We will try to counter their physical power, which we already know, with our own weapons,” he said, and apparently he has no knack issues to worry about. What is it that you actually do for a living?SSHCLF*****Dear SSHCLF,Thank you for your diligent research. We contacted Alan Shearer and he assured us that nobody knew anything about Spain (or England for that matter), but that the Fiver would sail through on a confident smile and a well-pressed shirt. So you really have done well on this – are you working for the NSA? Unfortunately it has all been in vain, however, because someone on Newsround asked Hope Powell if the England women’s team could beat the men’s team, and she answered “Absolutely, why not?” This is known in the trade as a “field day”. It is unlikely that we will have to write anything about the actual match after all.Yours, a relieved FiverLIVE ON BIG WEBSITE TONIGHTFollow MBM coverage of England 0-2 Spain with Georgina Turner from 7pm. QUOTE OF THE DAY"I will never forget that they used Tito [Vilanova]‘s illness to cause me damage, because it’s a lie that I never saw him in New York. I saw him once, and the reason I didn’t see him more often was because it wasn’t possible, and that wasn’t my fault. To say that I don’t wish the best of someone who was my colleague for so many years is very bad taste, micro niche finder review didn’t expect that" – Pep Guardiola explains why former employers Barcelona are mes que un club.TAT OF THE DAYWith spiralling costs and a nosediving economy, football clubs know that flogging tat has never been harder, forcing them to come up with ever more ingenious and revolutionary hawking tactics in order to expropriate pounds from wallets. But none has been as bold, enticing and downright haute as the limited-edition baseball cap supplied free with every purchase of an Arsenal away kit – for this is not just any old baseball cap, but one designed by the Carl Jenkinson. Of course, this could just be an elaborate piece of careers advice; rumours reach the Fiver that Gervinho has been commissioned for a loofah and Marouane Chamakh a carriage clock.FIVER LETTERS"I was delighted to appear to win an internal bet yesterday that you would christen your fantastic new ‘Footballers who say in interviews that their team will do well this season’ feature with a prediction from a Liverpool player. I was, however, disappointed to find that I had in fact lost that bet, having gambled that Deluded Optimism’s $tevie Mbe would be the man in question. If you decide to create a new feature based on footballers who gradually readjust their unrealistic ambitions for each passing month of the season, please let me know, as I fancy an accumulator on $tevie as follows: August – we can win the title; (later in) August – we can finish in the top four; October – we can get into Europe; December – we will stay up; March – I had never considered the manager’s job but when Mr Henry asked me to take over until the end of the season, I couldn’t say no" – Stephen Yoxall.“Sorry, but the Fiver’s Welsh cousin is wrong about Cardiff’s Croeso Stand (yesterday’s Bits and Bobs). In this context I think you’d translate the Croeso Stand as ‘The Welcome Stand’. And you can use ‘Croeso’ to mean ’You’re welcome’. Thus, Croeso” – Ian Morton-Jones.• Send your letters to the.boss@guardian.co.uk. Also, if you’ve nothing better to do you can also tweet the Fiver. Today’s winner of our prizeless letter o’ the day prize is: Stephen Yoxall.JOIN GUARDIAN SOULMATESWe keep trying to point out the utter futility of advertising an online dating service “for interesting people” in the Fiver to the naive folk who run Guardian Soulmates, but they still aren’t having any of it. So here you go – sign up here to view profiles of the kind of erudite, sociable and friendly romantics who would never dream of going out with you.BITS AND BOBSBrendan Rodgers can’t understand why Luis Suárez is so desperate to leave Liverpool. “I’ve been in communication with him through texts and conversations on the phone … We are in constant communication.” Ah.David Moyes has told José Mourinho that Wayne Rooney is not for sale after the Chelsea manager said he was a “player I like very much”. The United boss retorted: “Unless I was speaking double Dutch last week, we said Wayne Rooney is not for sale.”Talented Real Sociedad whelp Asier Illarremendi is on his way to Real Madrid in a £34m deal. “It was an offer we couldn’t refuse,” whimpered Illarremendi.Bradford City have got the funk on with Peterborough after Posh chairman Darragh MacAnthony revealed the club had an offer turned down for Nakhi Wells. “As a club, we don’t want to do our transfer business in public,” sniffed co-owner Mark Lawn, before doing just the opposite. “The offer was rejected out of hand.”Brentford have signed 37-year-old Villarreal veteran Javier Rodriguez Venta on a one-year deal.And Welsh minnows Prestatyn Town are on the march in Big Vase and will meet HNK Rijeka of Croatia in the second qualifying round after dumping out Liepajas Metalurgs in Latvia. “At Prestatyn we never ever know when we’re beaten. It’s a trait of ours,” hollered coach Chris Hughes.RECOMMENDED VIEWINGMartin Hinteregger gives a ball wings as he scores from his own half for Red Bull Salzburg against Schalke.STILL WANT fat-burning-furnace has been crunching the numbers in an investigation to show just how bare Mr Roy’s Premier League cupboard is.Tor-Kristian Karlsen runs the rule over Marco van Ginkel, Wilfried Bony and Jozy Altidore in his latest transfer window an@lysis piece.And Gary Neville has a little Q&A with Dom Fifield.SIGN UP TO THE FIVERWant your very own copy of our free tea-timely(ish) email sent direct to your inbox? Has your regular copy stopped arriving? Click here to sign up.JUMPING THE SHARKNADOGeorgina Turnerguardian.co.uk © 2013 Guardian News and Media Limited or its affiliated companies. All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds     Across the country, businesses have recovered while the public sector has struggled, and Detroit may be the most extreme example of a city’s dual fates diverging. BEIJING – World capitals on Wednesday braced for a new political order in Washington, as policymakers and analysts tried to assess the impact on foreign policy of a new Republican-led U.S. House, a diminished Democratic majority in the Senate and an American president many fear has been left wea… Big names and big productions with corporate tie-ins were one thread at the South by Southwest festival, but lesser known acts still make up its core. Constitutional amendments approved by wide margin in historic referendum. TAIPEI, TAIWAN – Despite nearly three years of warming relations across the narrow Taiwan Strait, Taiwanese President Ma Ying-jeou on Thursday pressed his case for continued American weapons sales to the island, including advanced U.S.-made fighter jets, saying Taiwan needs to negotiate with Chi… About 4.6 billion years ago, the solar system was little more than a tenuous disk of gas and dust. In the span of merely 10 million years, this soup evolved to form today’s massive, complex planets. In the intervening period, however, the solar system contained a mixture of intermediary bodies — small chunks of rock, the remnants of which today are known as asteroids. Although not much is known about the early composition of asteroids, some scientists suspect that such information may reveal an unexpected diversity of planetary bodies within the early solar system. Now a new study published this week in Science has found evidence that Vesta, the second-most-massive asteroid in the solar system, once harbored a dynamo — a molten, swirling mass of conducting fluid generating a magnetic field — resembling that in much larger planets like Earth. Researchers at MIT say the findings suggest that asteroids like Vesta may have been more than icy chunks of space debris.“We’re filling in the story of basically what happened during those first few million years of the solar system, when an entire solar system was dominated by objects like this,” says Roger Fu, a graduate student in MIT’s Department of Earth, Atmospheric and Planetary Sciences (EAPS), and the study’s first author. “These bodies are really like miniature planets.”“Vesta becomes now the smallest known planetary object to have generated a dynamo,” says co-author Benjamin Weiss, an associate professor of planetary sciences in EAPS. “You can imagine many asteroids in the early solar system were doing this.”Measuring a meteoriteMost or all of the planets in the inner solar system are thought to have generated dynamos at some point in their histories. In a dynamo, molten-hot iron flows within the core, generating a magnetic field that may last for millions of years. As a result, the rocks on the surface of a planetary body become magnetized, providing a record of a planet’s early history. Scientists have attempted to characterize the magnetization of meteorites — remnants of asteroids that have fallen to Earth — in order to reconstruct asteroid evolution. But a major challenge has been pinpointing the source of meteorites’ magnetization, which may be formed by any number of processes — such as plasmas from a meteoroid impact, or more mundane causes, like passing a magnet over a meteorite sample. Determining that a meteorite’s magnetic field is the result of an early dynamo is therefore a tricky problem.To google sniper problem, Fu and Weiss collaborated with researchers at the University of California at Berkeley, first to determine the magnetization and the age of a meteorite sample, then to check that the observed magnetic field was, in fact, due to an early dynamo. The group obtained a meteorite sample from Vesta that was originally discovered in Antarctica in 1981. The 50-gram sample, named ALHA81001, retains exceptional magnetic properties that scientists have been examining for years. Fu and his colleagues managed to acquire a one-gram sample of the rock for analysis. The team first examined the rock’s tiny crystals. When forming in a magnetic field, a rock’s ferromagnetic crystals align in the direction of a background field when the rock is heated. The group measured the alignment of these minerals, or the rock’s magnetic “moment.” The researchers progressively demagnetized the rock until they found the magnetization that they believed to be the oldest remnant of a magnetic field. The group’s next step was to determine the age of the rock. To do that, UC Berkeley researcher David Shuster analyzed the meteorite for evidence of argon. An isotope of argon called argon-40 is produced from the natural decay of potassium-40. A common technique for determining a rock’s age is to heat the rock and measure the amount of argon-40 released: The more argon-40, the older a rock may be. Through this technique, the researchers determined that the Vesta meteorite is 3.7 billion years old. Why a dynamo?However, because Vesta formed 4.5 billion years ago, any early dynamo must have decayed by the time the meteorite now known as ALHA81001 formed. So what is the origin of the field that magnetized this rock? Fu and Weiss believe that an early dynamo likely magnetized the surface of Vesta within the first 100 million years of the asteroid’s history, magnetizing surface rocks that then persisted over billions of years. When ALHA81001 formed 3.7 billion years ago, it would have also become magnetized due to exposure to fields emanating from the surrounding crust. Could the magnetization of Vesta’s rocks have been caused by anything other than a dynamo? To rule out other scenarios, the group analyzed the crystals in the meteorite sample to determine the rock’s cooling history. While large impacts might create a magnetic field, such impact-generated fields would only last a few tens of minutes, according to Fu — and if a rock were to become magnetized in such a short period of time, it would also cool equally quickly. To determine the cooling history — and therefore the magnetization period — of the meteorite sample, the group examined the tiny crystals on the rock’s surface — a technique developed by Timothy Grove, a professor of geology at MIT and a co-author of this week’s Science paper. They found that the rock experienced two periods of cooling: an initial rapid cooling, which produced fine crystals with excellent magnetic recording properties, followed by a much longer period of cooling. This longer cooling phase, Fu believes, is proof that the magnetic field observed in the rock is likely due not to an impact, but to a longer-lived field such as that expected for a dynamo. The evidence for a dynamo on Vesta lends support to the theory that other small bodies in the solar system may also have harbored similar dynamos, says Christopher Russell, a professor of geophysics and space physics at the University of California at Los Angeles. “The moon’s ancient dynamo is given added credibility by this measurement,” Russell says. “Another small body, Jupiter’s moon Ganymede, today appears to have an active dynamo in its core. This measurement makes that interpretation more credible as well.” “Vesta is so interesting, because it’s one of these building blocks that eventually formed the planets, and this is a remnant that’s still preserved and didn’t end up forming a planet,” Fu says. “It’s only 500 kilometers across, but it actually had many of the same global processes that the Earth has.” Why are we borne back ceaselessly to West Egg and Gatsby

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